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PTK2 Protein tyrosine Kinase 2 (PTK2) (Middle Region) Peptid

PTK2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513000

Kurzübersicht für PTK2 Protein tyrosine Kinase 2 (PTK2) (Middle Region) Peptid (ABIN5513000)

Target

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Spezies

Human

Quelle

  • 13
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    SWDSGGSDEA PPKPSRPGYP SPRSSEGFYP SPQHMVQTNH YQVSGYPGSH

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- PTK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    Hintergrund

    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined.

    Alias Symbols: FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK

    Protein Size: 1052

    Gen-ID

    5747

    NCBI Accession

    NM_001199649, NP_001186578

    UniProt

    Q05397
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